She is charged in a single-count criminal complaint with conspiracy to distribute cocaine,methamphetamine,heroin and marijuana in the US.
The Justice Department also accuses her of helping her husband escape from a Mexican prison in 2015 and participating in the planning of a second prison escape before Guzman was extradited to the US in January 2017.
Aispuro remained in custody,and it was not immediately clear if she had an attorney who could comment on the allegations.
As Mexico’s most powerful drug lord,Guzmanescaped through an entry under the shower in his cell to a 1.6-kilometre-long lighted tunnel with a motorcycle on rails. The planning for the escape was extensive,prosecutors say,with his wife playing a key role.
Court papers charge that Aispuro worked with Guzman’s sons and a witness,who is now cooperating with the US government,to organise the construction of the underground tunnel that Guzman used to escape from the Altiplano prison in Mexico to prevent him from being extradited to the US.
The plot included purchasing a piece of land near the prison,firearms and an armoured truck and smuggling him a GPS watch so they could “pinpoint his exact whereabouts so as to construct the tunnel with an entry point accessible to him,” the court papers say.